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BioTechnology QUESTION #10562
Question 1
In eukaryotic cells, fatty acid synthesis occurs in the cytoplasm, whereas fatty acid degradation (β-oxidation) occurs in:
  • The nucleus
  • The endoplasmic reticulum
  • The peroxisome✔️
  • The Golgi apparatus
Correct Answer Explanation
In eukaryotes, β-oxidation of fatty acids occurs in the peroxisome (and to a lesser extent, mitochondria). Separating synthesis (cytoplasm) from degradation (peroxisome) prevents futile cycling. Peroxisomes contain catalase and peroxidase that handle the H₂O₂ generated during oxidation. This compartmentalisation is a key metabolic control strategy in eukaryotes.