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OPRA Biomedical Sciences QUESTION #3798
Question 1
Which metabolic byproduct accumulating in muscle tissue is primarily responsible for the sensation of muscle fatigue during intense exercise?
  • Ischaemia due to atherosclerotic plaques
  • Accumulation of lactic acid✔️
  • Lack of sufficient ATP molecules
  • Accumulation of carbon dioxide
Correct Answer Explanation
During intense exercise, anaerobic glycolysis produces lactic acid, which lowers intracellular pH and contributes to muscle fatigue and impaired contractility.