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OPRA Medicinal Chemistry and Biopharmaceutics QUESTION #3817
Question 1
Which analytical technique can be used to resolve a single enantiomer from a racemic mixture?
  • Acid-base reaction
  • Boiling point
  • Chromatography✔️
  • Infrared spectrometry
Correct Answer Explanation
Chiral chromatography (e.g., HPLC with chiral stationary phases) can separate enantiomers. Boiling point and IR are identical for enantiomers.