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OPRA Medicinal Chemistry and Biopharmaceutics QUESTION #3827
Question 1
What is the purpose of adding sodium metabisulphite to epinephrine (adrenaline) injection formulations?
  • Suspending agent
  • Fungicide
  • Antioxidant✔️
  • Bactericide
Correct Answer Explanation
Sodium metabisulphite is an antioxidant added to prevent the oxidative degradation of epinephrine, which is highly susceptible to oxidation. It preserves potency and shelf life.