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OPRA Medicinal Chemistry and Biopharmaceutics QUESTION #3828
Question 1
Within what temperature range should total parenteral nutrition (TPN) solutions be stored to maintain stability and prevent microbial growth?
  • $1^\circ\text{C}$ and $4^\circ\text{C}$
  • $2^\circ\text{C}$ and $8^\circ\text{C}$✔️
  • $15^\circ\text{C}$ and $20^\circ\text{C}$
  • $25^\circ\text{C}$ and $35^\circ\text{C}$
Correct Answer Explanation
TPN solutions should be stored refrigerated between $2^\circ\text{C}$ and $8^\circ\text{C}$ according to guidelines, but practically $1^\circ\text{C}$–$4^\circ\text{C}$ is the accepted optimal refrigeration range for these preparations.