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OPRA Pharmacokinetics and Pharmacodynamics QUESTION #3829
Question 1
A paediatric patient weighing $30$ kg is prescribed metronidazole $250$ mg every $8$ hours. Each mL of a $500\ \text{mg}/500\ \text{mL}$ ampoule contains $0.135\ \text{mmol/mL}$ sodium. What is the total sodium intake over $24$ hours?
  • $33.8$ mmol
  • $101.3$ mmol✔️
  • $202.5$ mmol
  • $1852$ mmol
Correct Answer Explanation
Three doses of $250$ mg each $= 3 \times 250\ \text{mL}$ of the solution. Volume per dose $= 250\ \text{mL}$, total $= 750\ \text{mL}$. Sodium $= 750 \times 0.135 = 101.3\ \text{mmol}$.