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OPRA Pharmacokinetics and Pharmacodynamics QUESTION #3837
Question 1
A $2$ g vial is added to $500$ mL IV fluid administered at $125$ mL/hour. Assuming a constant infusion rate, what dose of cefalotin does the patient receive per minute?
  • $8.33$ mg✔️
  • $83.3$ mg
  • $500$ mg
  • $833$ mg
Correct Answer Explanation
Concentration $= \dfrac{2000\ \text{mg}}{500\ \text{mL}} = 4\ \text{mg/mL}$. Rate $= \dfrac{125\ \text{mL/hr}}{60} = 2.083\ \text{mL/min}$. Dose/min $= 2.083 \times 4 = 8.33\ \text{mg/min}$.