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OPRA Therapeutics and Patient Care QUESTION #3913
Question 1
Which of the following recommendations regarding aciclovir use for herpes zoster (shingles) is LEAST appropriate?
  • It will be less effective if started more than 72 hours after the onset of the rash
  • It will reduce the duration of herpes zoster related pain
  • It should be taken five times a day for 7 days
  • Fluid intake should be kept to a minimum during the course of treatment✔️
Correct Answer Explanation
Patients taking aciclovir should maintain adequate hydration, as the drug can crystallise in renal tubules causing nephrotoxicity. Restricting fluid intake is dangerous and incorrect.