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Nursing QUESTION #9233
Question 1
A critically ill patient develops Disseminated Intravascular Coagulation (DIC). Which laboratory profile is MOST consistent with this diagnosis?
  • Elevated PT, elevated aPTT, elevated fibrinogen, decreased D-dimer, decreased platelets
  • Elevated PT, elevated aPTT, decreased fibrinogen, elevated D-dimer, decreased platelets✔️
  • Normal PT, elevated aPTT, elevated fibrinogen, elevated D-dimer, elevated platelets
  • Decreased PT, decreased aPTT, elevated fibrinogen, decreased D-dimer, elevated platelets
Correct Answer Explanation
Correct Answer: B

DIC Laboratory Findings:
Lab TestDIC ResultReason
Prothrombin Time (PT)↑ ElevatedClotting factors consumed
aPTT↑ ElevatedClotting factors consumed
Fibrinogen↓ DecreasedConsumed in widespread clotting
D-dimer↑ ElevatedFibrin degradation products from clot lysis
Platelets↓ DecreasedConsumed in microthrombi formation
Peripheral smearSchistocytesRed cell fragmentation from fibrin strands
DIC is a paradox: simultaneous clotting AND bleeding. Common ICU triggers include sepsis, trauma, obstetric emergencies, and malignancy. Management includes treating the underlying cause, FFP, cryoprecipitate, and platelets.