Correct Answer: B — \(10.5 \text{ mL/hr}\)

Step-by-step calculation:

Step 1: Calculate the required dose in mcg/min:
\[\text{Dose} = 0.1 \text{ mcg/kg/min} \times 70 \text{ kg} = 7 \text{ mcg/min}\]

Step 2: Convert to mcg/hr:
\[7 \text{ mcg/min} \times 60 = 420 \text{ mcg/hr}\]

Step 3: Calculate concentration of solution:
\[\text{Concentration} = \frac{4 \text{ mg}}{250 \text{ mL}} = \frac{4000 \text{ mcg}}{250 \text{ mL}} = 16 \text{ mcg/mL}\]

Step 4: Calculate infusion rate:
\[\text{Rate} = \frac{420 \text{ mcg/hr}}{16 \text{ mcg/mL}} = 26.25 \text{ mL/hr}\]

Wait — rechecking: correct answer is 26.25 mL/hr → option A is correct.

Correct Answer is A — \(26.25 \text{ mL/hr}\)

Norepinephrine is the vasopressor of choice in septic shock (SSC guidelines). Always verify drug calculations using the formula: \[\text{Rate (mL/hr)} = \frac{\text{Dose (mcg/kg/min)} \times \text{Weight (kg)} \times 60}{\text{Concentration (mcg/mL)}}\]