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Nursing QUESTION #9257
Question 1
A nurse is preparing to administer the pentavalent vaccine to a 6-week-old infant as per Pakistan's Expanded Programme on Immunization (EPI) schedule. The pentavalent vaccine protects against which combination of diseases?
  • Diphtheria, Tetanus, Pertussis, Polio, Measles
  • Diphtheria, Tetanus, Pertussis, Hepatitis B, Haemophilus influenzae type b (Hib)✔️
  • Tuberculosis, Polio, Tetanus, Hepatitis B, Measles
  • Diphtheria, Tetanus, Pertussis, Pneumococcal, Rotavirus
Correct Answer Explanation

Pakistan EPI Schedule (current):

AgeVaccines
BirthBCG, OPV-0, Hepatitis B (birth dose)
6 weeksPentavalent (DTP-HepB-Hib), OPV-1, PCV-1, Rotavirus-1, IPV-1
10 weeksPentavalent-2, OPV-2, PCV-2, Rotavirus-2
14 weeksPentavalent-3, OPV-3, PCV-3, IPV-2
9 monthsMeasles-1, Vitamin A (1st dose)
15 monthsMeasles-2 (MMR)

Pentavalent vaccine = 5-in-1 vaccine protecting against:

  1. Diphtheria
  2. Tetanus
  3. Pertussis (whooping cough)
  4. Hep B (Hepatitis B)
  5. Hib (Haemophilus influenzae type b)

Contraindications: Previous anaphylaxis to vaccine component, progressive neurological disorder (for pertussis component), severe febrile illness (defer, not contraindicate).

Cold chain: Pentavalent stored at \(2{-}8°C\); never frozen (freeze-sensitive).