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Long-term corticosteroid therapy mimics endogenous excess cortisol, producing iatrogenic Cushing's Syndrome:
| System | Effect of Excess Corticosteroids |
|---|---|
| Metabolic | Hyperglycemia (steroid-induced diabetes) |
| Appearance | Moon face, buffalo hump, central obesity, striae |
| Skeletal | Osteoporosis, vertebral fractures |
| Immune | Immunosuppression β increased infection risk (mask fever!) |
| Cardiovascular | Hypertension, fluid retention, edema |
| Electrolytes | Hypokalemia, hypernatremia |
| GI | Peptic ulcer formation |
Critical nursing point: Patients on long-term steroids should never abruptly stop β risk of adrenal crisis (Addisonian crisis). Taper dosage gradually.
Using the Principle of Calorimetry: Heat lost by metal = Heat gained by (water + calorimeter).
$m_m s_m (100 - 21.5) = (m_w s_w + m_c s_c) (21.5 - 8.4)$
$0.192 \times s_m \times 78.5 = (0.24 \times 4184 + 0.128 \times 394) \times 13.1$
$15.072 s_m = (1004.16 + 50.432) \times 13.1 = 1054.592 \times 13.1 = 13815.15$
$s_m \approx 916.6 \text{ J kg}^{-1}\text{K}^{-1}$
Complete the analogy: Order is the law of civilization as chaos is the law of the ______.
This is a classic contrast: civilization represents order, while the wilderness (nature untamed) represents chaos. The phrase evokes the idea that human society creates order, whereas wild nature is chaotic.
Complete the analogy: Blueprint is to architect as algorithm is to ______.
An architect uses a blueprint to design a building. Similarly, a programmer uses an algorithm to design a computer program. While engineers and mathematicians also use algorithms, the closest analogy is with a programmer.
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