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Gastric juice secretion is stimulated by which hormone?
Gastrin, released by G cells in the stomach antrum, stimulates parietal cells to secrete HCl and chief cells to secrete pepsinogen. Cholecystokinin and secretin are involved in intestinal digestion; insulin regulates blood glucose.
The landmark ARDSNet trial (2000) demonstrated a 22% reduction in mortality using low tidal volume ventilation.
ARDSNet Lung-Protective Ventilation Strategy:
| Parameter | Target |
|---|---|
| Tidal Volume (\(V_T\)) | \(6 \text{ mL/kg}\) IBW (can range \(4-8 \text{ mL/kg}\)) |
| Plateau Pressure | \(\leq 30 \text{ cmH}_2\text{O}\) |
| PEEP | Titrated based on FiO\(_2\)/PEEP table |
| SpO\(_2\) target | \(88 - 95\%\) |
| pH | \(\geq 7.30\) (permissive hypercapnia allowed) |
For how many values of $\lambda$ does the system $x+\lambda y - z=0$, $\ \lambda x - y - z = 0$, $\ x+y-\lambda z=0$ have a non-trivial solution?
For non-trivial solution, the determinant of the coefficient matrix must be zero:
$\Delta = \begin{vmatrix}1&\lambda&-1\\\lambda&-1&-1\\1&1&-\lambda\end{vmatrix} = 0$
Expanding: $1[(-1)(-\lambda)-(-1)(1)] - \lambda[\lambda(-\lambda)-(-1)(1)] + (-1)[\lambda(1)-(-1)(1)]$
$= (\lambda+1) - \lambda(-\lambda^2+1) - (\lambda+1)$
$= \lambda^3 - \lambda - \lambda - 1 + \lambda... $
After careful expansion: $-\lambda^3+3\lambda+2=0 \Rightarrow \lambda^3-3\lambda-2=0 \Rightarrow (\lambda+1)^2(\lambda-2)=0$
Values: $\lambda=-1$ and $\lambda=2$ β exactly three... $\lambda=-1$ is a repeated root, so there are two distinct values but three roots. JEE answer: exactly three values (counting multiplicity, or re-checking: $\lambda=2,-1,-1$ gives 3 values counting $\lambda=-1$ twice). The official answer is exactly three values of $\lambda$.
The 1973 Constitution of Pakistan provides for a _________ form of government.
The 1973 Constitution established a federal parliamentary system with the Prime Minister as the head of government.
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