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QUESTION #10147
Question 1
A 50-year-old man sustains a mid-shaft fracture of the femur. Radiographs at 6 weeks show a bridge of woven bone (external callus) at the fracture site. Which structure is primarily responsible for producing this bridging callus?
Correct Answer Explanation
The inner (cambium) layer of the periosteum is richly osteogenic and proliferates rapidly after a fracture, laying down subperiosteal (external) callus that bridges the fracture ends. The endosteum contributes to internal callus formation, but bridging external callus is chiefly periosteal in origin — the basis for careful periosteal preservation during open fracture fixation.
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