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MBBS QUESTION #10219
Question 1
Glucose entry into most peripheral cells (e.g., via GLUT4/GLUT1 transporters) does not require ATP directly but does require a specific carrier protein and shows saturation kinetics. This transport process is best classified as:
  • Simple diffusion
  • Facilitated diffusion✔️
  • Primary active transport
  • Secondary active (co-)transport
Correct Answer Explanation
Facilitated diffusion moves solutes down their concentration gradient using a specific membrane carrier, without direct ATP consumption, but unlike simple diffusion it is saturable and carrier-specific — the mechanism used by most glucose transporters (GLUTs) in peripheral tissues.