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MBBS QUESTION #10269
Question 1
Cholecystokinin (CCK), released from duodenal I cells in response to fatty acids and amino acids in the chyme, has which combination of principal physiological actions?
  • Stimulates gallbladder contraction and pancreatic enzyme secretion, while relaxing the sphincter of Oddi to allow bile and pancreatic juice to enter the duodenum✔️
  • Stimulates gastric acid secretion as its primary effect
  • Inhibits pancreatic enzyme secretion
  • Stimulates salivary gland secretion
Correct Answer Explanation
CCK coordinates the digestive response to fat and protein by contracting the gallbladder, stimulating pancreatic acinar enzyme secretion, and relaxing the sphincter of Oddi — ensuring bile and pancreatic enzymes reach the duodenum precisely when needed for fat and protein digestion.