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MBBS QUESTION #10272
Question 1
A patient presents with spastic weakness, hyperreflexia, increased muscle tone, and a positive Babinski sign (extensor plantar response), without significant muscle wasting. This clinical pattern localizes the lesion to which level?
  • An upper motor neuron lesion✔️
  • A lower motor neuron lesion
  • The neuromuscular junction
  • Skeletal muscle itself (a primary myopathy)
Correct Answer Explanation
Upper motor neuron lesions (e.g., stroke affecting the corticospinal tract) classically produce spasticity, hyperreflexia, and an extensor plantar (Babinski) response, with relatively preserved muscle bulk, in contrast to lower motor neuron lesions which cause flaccid weakness with wasting and fasciculations.