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MBBS QUESTION #10290
Question 1
Chvostek's sign (facial muscle twitching on tapping over the facial nerve) and Trousseau's sign (carpal spasm on blood pressure cuff inflation) both indicate neuromuscular irritability (tetany), classically seen in which electrolyte/hormonal disturbance?
  • Hypocalcemia, as in hypoparathyroidism✔️
  • Hypercalcemia
  • Hyperkalemia
  • Hypernatremia
Correct Answer Explanation
Low ionized calcium increases neuronal membrane excitability by lowering the threshold for Na+ channel activation, producing spontaneous neuromuscular irritability — clinically demonstrated by Chvostek's and Trousseau's signs, classically seen in hypoparathyroidism or other causes of hypocalcemia.