Home › MCQs › MBBS › Question #10292
Back to Questions
MBBS QUESTION #10292
Question 1
Conn's syndrome (primary hyperaldosteronism, typically from an adrenal adenoma) classically produces which combination of biochemical findings?
  • Hypertension, hypokalemia, and metabolic alkalosis, with suppressed plasma renin activity✔️
  • Hypotension with hyperkalemia
  • Elevated plasma renin with low aldosterone
  • Entirely normal electrolytes with isolated hypertension and no biochemical abnormality
Correct Answer Explanation
Autonomous aldosterone excess drives renal sodium retention (hypertension) with increased potassium and hydrogen ion excretion (hypokalemia and metabolic alkalosis); the resulting volume expansion suppresses renin-angiotensin activity, giving the classic biochemical triad plus low renin that distinguishes primary from secondary hyperaldosteronism.