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MBBS QUESTION #10297
Question 1
A couple undergoing infertility evaluation finds a semen analysis with a normal sperm count and normal morphology, but markedly reduced forward (progressive) motility — asthenozoospermia. This abnormality most directly impairs:
  • Spermatogenesis (sperm production) itself
  • The sperm's ability to traverse the female reproductive tract and successfully reach and penetrate the oocyte✔️
  • Testosterone secretion by Leydig cells
  • The processes of erection and ejaculation
Correct Answer Explanation
Since sperm count and morphology are normal, the fertility-limiting problem lies in the sperm's functional motility — required to swim through cervical mucus, the uterus, and fallopian tube, and to penetrate the oocyte's zona pellucida — rather than in sperm production or ejaculatory mechanics.