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MBBS QUESTION #10305
Question 1
Glycogen, the primary storage form of glucose in liver and skeletal muscle, is a branched polysaccharide of glucose units linked predominantly by which glycosidic bonds, with branch points formed by a second bond type?
  • $\alpha$-1,4 linkages in the main chain, with $\alpha$-1,6 linkages at branch points✔️
  • $\beta$-1,4 linkages throughout, identical to cellulose
  • $\alpha$-1,2 linkages exclusively
  • $\beta$-1,6 linkages exclusively
Correct Answer Explanation
Glycogen's $\alpha$-1,4 glycosidic bonds form long linear glucose chains, while $\alpha$-1,6 branch points (introduced by the branching enzyme) create a highly branched structure that allows rapid, simultaneous glucose release from multiple chain ends during glycogenolysis.