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MBBS QUESTION #10309
Question 1
Immunoglobulins (antibodies), central to humoral immunity, are structurally composed of:
  • A single polypeptide chain folded into multiple domains
  • Two identical heavy chains and two identical light chains, linked together by disulfide bonds✔️
  • Four identical heavy chains with no light chains
  • One heavy chain paired with four light chains
Correct Answer Explanation
The basic immunoglobulin unit is a Y-shaped structure of two heavy chains and two light chains held together by interchain disulfide bonds, with variable regions at the tips of the 'Y' providing antigen specificity.