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MBBS QUESTION #10332
Question 1
A child presents with bowed legs, widened wrists and costochondral joints ('rachitic rosary'), and delayed fontanelle closure. This is most consistent with rickets due to deficiency of which vitamin, which normally promotes intestinal calcium and phosphate absorption and bone mineralization?
  • Vitamin A
  • Vitamin D✔️
  • Vitamin E
  • Vitamin K
Correct Answer Explanation
Vitamin D (as its active metabolite, calcitriol) promotes intestinal absorption of calcium and phosphate and supports normal bone mineralization; its deficiency in growing children impairs mineralization of the growth plate and osteoid, producing the characteristic skeletal deformities of rickets.