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MDCAT Biology QUESTION #4330
Question 1
According to the Lock and Key model, the active site is regarded as:
  • Rigid and specific✔️
  • Flexible and specific
  • Rigid and non-specific
  • Flexible and non-specific
Correct Answer Explanation
The Lock and Key model (Fischer, 1894) proposes that the enzyme active site has a fixed, rigid shape that is exactly complementary to a specific substrate — rigid and specific.