Home › MCQs › MDCAT Biology › Question #7774
Back to Questions
MDCAT Biology QUESTION #7774
Question 1

Sickle cell anemia results from what molecular abnormality?

  • Reduced oxygen capacity
  • Linkage between polypeptide chains
  • Single amino acid substitution in hemoglobin✔️
  • Viral infection of RNA viruses
Correct Answer Explanation

Sickle cell anemia is caused by a point mutation (GAG → GTG) in the β-globin gene, replacing glutamate (Glu) with valine (Val) at position 6, causing hemoglobin polymerization.